The City of La Marque is a located in the south central portion of Galveston County and is bounded on the north and east by Texas City, south by Bayou Vista and Hitchcock, and west by unincorporated Galveston County. La Marque's ideal location puts in within comfortable driving distance to Houston and Galveston.

La Marque’s history extends back to the days of the Republic of Texas. Located along the banks of Highland Bayou, the largely rural town was settled and named Highlands. During the Civil War, soldiers stopped on route between Galveston and Houston to purchase buttermilk, earning Highlands the nickname “Buttermilk Station.” During the 1890’s it was learned that another community existed with the same name. Postmistress Madam St. Ambrose renamed the town La Marque, a French term for “the mark.”